Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.37 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314133 | 0.79 | CAPN1 (0.62) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL25314124 | 0.79 | CAPN1 (0.62) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL24842411 | 0.75 | CAPN1 (0.64) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL14326980 | 0.69 | TSHR (0.52) | MAPK1GRNSORT1 | |
| SCHEMBL23961654 | 0.69 | CAPN1 (0.66) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL19391046 | 0.68 | CAPN1 (0.52) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL22273549 | 0.68 | CAPN1 (0.52) | CAPN1CAPN9CTSBMAPK1CTSL | |
| SCHEMBL19391018 | 0.68 | CAPN1 (0.40) | CAPN1CAPN9CTSBMAPK1GRN | |
| SCHEMBL22392911 | 0.67 | CAPN1 (0.53) | CAPN1CAPN9CTSBMAPK1PSEN1 | |
| SCHEMBL19390995 | 0.67 | CAPN1 (0.47) | CAPN1CAPN9CTSBMAPK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4463445-B1 | COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF DISEASES ASSOCIATED WITH IMPAIRED ?-GALACTOSIDASE ACTIVITY | DORPHAN S A (CH) | 2025-10-01 | — | — | EP | claimed |