SCHEMBL31691235

SCHEMBL31691235

COCC(C)(C)c1ccc(OC)c(S(=O)(=O)NC(=O)c2ccc(Cn3cccn3)c(OC)n2)c1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 19/20 0.40
▸ KAT6A Q92794 19/20 0.40
▸ KAT6B Q8WYB5 14/20 0.40
▸ KAT5 Q92993 9/20 0.38
▸ KAT8 Q9H7Z6 9/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31172620 0.94 KAT7 (0.41) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31172521 0.92 ALPL (0.43) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31172753 0.92 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516894 0.91 KAT7 (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516648 0.90 ALPL (0.44) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516638 0.90 KAT7 (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516693 0.90 KAT7 (0.40) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516717 0.87 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31172580 0.87 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31516642 0.87 KAT7 (0.38) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304535-A1 KAT6 Inhibitors BEIGENE SWITZERLAND GMBH (CH) 2025-10-02 — — US disclosed
WO-2025201504-A1 KAT6 INHIBITORS BEIGENE (SUZHOU) CO., LTD. (CN) 2025-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304535-A1 KAT6 Inhibitors KAT6A, KAT6B, KAT2A KAT7 4/4885KAT6A 1/4885KAT6B 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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