Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 15/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691866 | 0.82 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL31543284 | 0.81 | MAOB (0.37) | MAPK1CYP1A2 | |
| SCHEMBL31691822 | 0.80 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL31543410 | 0.80 | MAPK1 (0.50) | MAPK1 | |
| Hydrochloric Acid SCHEMBL31543151 | 0.78 | MAPK1 (0.49) | MAPK1 | |
| SCHEMBL31691901 | 0.78 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL31543142 | 0.77 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL26891345 | 0.77 | MAPK1 (0.47) | MAPK1 | |
| SCHEMBL31691995 | 0.77 | MAPK1 (0.37) | MAPK1 | |
| SCHEMBL31692036 | 0.76 | MAPK1 (0.48) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | BIOGEN MA INC. | 2025-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250304577-A1 | TYK2 INHIBITORS | TYK2, JAK2, JAK1 | MAPK1 228/4885CYP1A2 2380/4885CHRM4 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.