Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214031 | 1.00 | TSHR (0.46) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL600893 | 0.85 | TDP1 (0.46) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29936995 | 0.85 | TDP1 (0.46) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL29653309 | 0.84 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4ATM | |
| SCHEMBL2477068 | 0.84 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4ATM | |
| SCHEMBL3633645 | 0.84 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL31592017 | 0.84 | TSHR (0.52) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| Hydrochloric Acid SCHEMBL28508306 | 0.83 | TDP1 (0.44) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL107162 | 0.82 | TDP1 (0.50) | TSHRALDH1A1CYP3A4CYP1A2ATM | |
| SCHEMBL864500 | 0.82 | TSHR (0.50) | TSHRMAPK1ALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025202889-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2025-10-02 | — | — | WO | disclosed |