SCHEMBL31694488

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	C5AR1	P21730	2/20	0.58

▸	GLP1R	P43220	10/20	0.53

▸	SCTR	P47872	1/20	0.53

▸	TFPI	P10646	1/20	0.53

▸	MC4R	P32245	1/20	0.53

▸	GCGR	P47871	1/20	0.50

▸	IL23R	Q5VWK5	3/20	0.49

▸	KLK7	P49862	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Histatin 5 SCHEMBL31694496	0.93	GLP1R (0.57)	C5AR1GLP1RSCTRTFPIMC4R
SCHEMBL29624477	0.91	MC4R (0.50)	C5AR1GLP1RSCTRTFPIMC4R
SCHEMBL29536767	0.91	C5AR1 (0.56)	C5AR1GLP1R
SCHEMBL30956348	0.90	GLP1R (0.51)	C5AR1GLP1RSCTRGCGRKLK7
SCHEMBL30773913	0.90	GLP1R (0.53)	C5AR1GLP1RSCTRMC4RGCGR
SCHEMBL29586707	0.90	C5AR1 (0.47)	C5AR1GLP1RSCTRMC4R
SCHEMBL29716050	0.90	GLP1R (0.62)	C5AR1GLP1RSCTRTFPIGCGR
SCHEMBL2192357	0.90	C5AR1 (0.50)	C5AR1GLP1RSCTR
SCHEMBL2192350	0.90	C5AR1 (0.50)	C5AR1GLP1RSCTR
SCHEMBL29461974	0.89	NPY4R (0.51)	C5AR1GLP1RSCTRMC4RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-RE50618-E1	Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same	PHARMAIN CORPORATION (US)	2025-10-07	—	—	US	disclosed