SCHEMBL31694841

SCHEMBL31694841

COc1ccc(Oc2ccc(C(F)(F)F)cc2Cl)cc1N

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.63
RAB9A P51151 1/20 0.63
MAPT P10636 3/20 0.59
NPSR1 Q6W5P4 1/20 0.59
LMNA P02545 1/20 0.52
ATM Q13315 1/20 0.52
FFAR1 O14842 5/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 1/20 0.49
THRB P10828 1/20 0.49
TTR P02766 1/20 0.48
PPOX P50336 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HTR2A P28223 4/20 0.47
SLC6A4 P31645 4/20 0.47
KCNH2 Q12809 4/20 0.47
ESRRA P11474 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232669 1.00 L3MBTL1 (0.63) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL10838585 0.90 L3MBTL1 (0.58) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL8812673 0.87 L3MBTL1 (0.52) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL10605270 0.87 L3MBTL1 (0.52) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL24750320 0.84 L3MBTL1 (0.65) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL31694850 0.84 L3MBTL1 (0.65) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL11238861 0.84 L3MBTL1 (0.68) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL24749630 0.84 L3MBTL1 (0.68) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL30768368 0.84 L3MBTL1 (0.68) L3MBTL1RAB9AMAPTNPSR1LMNA
SCHEMBL9373448 0.83 L3MBTL1 (0.52) L3MBTL1RAB9AMAPTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed