⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172304 | 1.00 | — | — | |
| SCHEMBL3169531 | 1.00 | — | — | |
| SCHEMBL8582042 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL9001237 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL8582044 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL936905 | 0.76 | NR4A1 (0.41) | — | |
| SCHEMBL936907 | 0.76 | NR4A1 (0.41) | — | |
| SCHEMBL3454104 | 0.76 | NR4A1 (0.41) | — | |
| SCHEMBL20354575 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL3169541 | 0.74 | NR4A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737303-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH LLC (US) | 2010-06-15 | — | — | US | disclosed |
| US-20100016639-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | WYETH (US) | 2010-01-21 | — | — | US | disclosed |
| US-7598422-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2009-10-06 | — | — | US | disclosed |
| EP-2010478-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | Wyeth (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007127108-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | WYETH (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2007-10-25 | — | — | US | disclosed |
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-5424333-A | Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines | ROHM AND HAAS COMPANY (US) | 1995-06-13 | — | — | US | disclosed |
| EP-0361645-B1 | ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE | ROHM AND HAAS COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0234944-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ACYL-N'-ALKYLCARBONYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0361645-A2 | Organic hydrazine derivatives for pharmaceutical use | ROHM AND HAAS COMPANY (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |