Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1078112 | 0.80 | CA1 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL9442358 | 0.78 | GSR (0.47) | ALOX15KMT2ADPP8DPP9FOLH1 | |
| SCHEMBL7963433 | 0.74 | — | — | |
| SCHEMBL28829367 | 0.74 | — | — | |
| SCHEMBL2225373 | 0.74 | CYP2C9 (0.38) | ALOX15BLMPMP22KMT2ADPP4 | |
| SCHEMBL7428214 | 0.72 | — | — | |
| SCHEMBL28867965 | 0.71 | KMT2A (0.50) | ALOX15BLMPMP22KMT2A | |
| SCHEMBL28867964 | 0.71 | KMT2A (0.50) | ALOX15BLMPMP22KMT2A | |
| SCHEMBL349164 | 0.71 | ENPEP (0.46) | BLMPMP22KMT2AFOLH1ENPEP | |
| SCHEMBL8209380 | 0.70 | KMT2A (0.54) | ALOX15BLMPMP22KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660507-B2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | MILLENNIUM PHARM INC (US) | 2017-01-04 | — | — | EP | disclosed |
| EP-1660507-B9 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2010-03-24 | — | — | EP | disclosed |
| EP-1660507-B1 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON INC (US) | 2009-08-05 | — | — | EP | disclosed |