Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119770 | 1.00 | MPO (0.66) | MPOCYP1A2CYP2D6ELANEABCB1 | |
| SCHEMBL11094766 | 0.86 | MPO (0.53) | MPOABCB1METAP1CYP19A1CYP11B2 | |
| SCHEMBL31285043 | 0.82 | MPO (0.66) | MPOCYP1A2CYP2D6ELANEABCB1 | |
| SCHEMBL29248715 | 0.81 | MPO (0.47) | MPOCYP1A2CYP2D6METAP1CYP19A1 | |
| SCHEMBL3277069 | 0.81 | MPO (0.45) | MPOKDM4EALDH1A1 | |
| SCHEMBL27001686 | 0.81 | MPO (0.64) | MPOCYP1A2CYP2D6ELANEABCB1 | |
| SCHEMBL6552114 | 0.81 | MPO (0.64) | MPOCYP1A2CYP2D6ELANEABCB1 | |
| SCHEMBL30640469 | 0.81 | MPO (0.64) | MPOCYP1A2CYP2D6ELANEABCB1 | |
| SCHEMBL17108416 | 0.78 | MPO (0.59) | MPOCYP1A2CYP2D6METAP1CYP19A1 | |
| SCHEMBL15818200 | 0.78 | MPO (0.74) | MPOCYP1A2CYP2D6ELANEABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782977-A1 | CYCLOPROPANATION METHOD AND REAGENT | Fundació Privada Institut Català d'Investigació Química (ICIQ) (ES) | 2021-02-24 | — | — | EP | disclosed |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-09-15 | — | — | US | disclosed |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-09-15 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-06-16 | — | — | US | disclosed |
| WO-2014207766-A1 | OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | disclosed |
| WO-2014207766-A1 | OXONE-ACETONE MEDIATED METAL FREE PREPARATION OF SYN-DIOLS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-31 | — | — | WO | disclosed |
| US-8592458-B2 | Alpha7 nicotinic receptor selective ligands | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20120094943-A1 | ALPHA 7 NICOTINIC RECEPTOR SELECTIVE LIGANDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-04-19 | — | — | US | disclosed |
| EP-1073640-A1 | NAPHTHALENE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-6054474-A | Heterocyclic compounds for the treatment of pain and use thereof | BIOCHEM PHARMA, INC. (CA) | 2000-04-25 | — | — | US | disclosed |
| US-5990104-A | INHIBITING NMDA RECEPTOR ACTIVATION BY ADMINISTERING DERIVATIVES OF GIVEN FORMULA, SUCH AS 5,6,7,8,9,11,12-HEPTAHYDRO-3-HYDROXY-5-METHYL-10-THIA-5,11 -METHANOBENZOCYCLODECEN-13-AMINE (SULPHAZOCINE) | BIOCHEM PHARMA, INC. (CA) | 1999-11-23 | — | — | US | disclosed |
| WO-1999054309-A1 | NAPHTHALENE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-28 | — | — | WO | disclosed |
| EP-0850234-A1 | NOVEL HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF PAIN AND USE THEREOF | BIOCHEM PHARMA INC (CA) | 1998-07-01 | — | — | EP | disclosed |
| EP-0840731-A1 | POLYCYCLIC ALCALOID-DERIVATIVES AS NMDA-RECEPTOR ANTAGONISTS | BIOCHEM PHARMA INC (CA) | 1998-05-13 | — | — | EP | disclosed |
| WO-1997003979-A1 | POLYCYCLIC ALCALOID-DERIVATIVES AS NMDA-RECEPTOR ANTAGONISTS | BIOCHEM PHARMA INC. (CA) | 1997-02-06 | — | — | WO | disclosed |
| WO-1997003978-A1 | NOVEL HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF PAIN AND USE THEREOF | BIOCHEM PHARMA INC. (CA) | 1997-02-06 | — | — | WO | disclosed |
| US-5491233-A | Catalytic asymmetric reduction of trisubstituted olefins | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-02-13 | — | — | US | disclosed |
| US-5442119-A | Catalytic asymmetric reduction of trisubstituted olefins | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094943-A1 | ALPHA 7 NICOTINIC RECEPTOR SELECTIVE LIGANDS | CHRNA7, CHRNA10, CHRNA5 | MPO 2427/4885CYP1A2 1218/4885CYP2D6 2319/4885 |
| US-20160168114-A1 | Oxone-Aceton Mediated Metal Free Preparation of Syn-Diols | SQLE, OXER1, OXA1L | MPO 1767/4885CYP1A2 147/4885CYP2D6 102/4885 |
| US-10774060-B2 | Oxone-aceton mediated metal free preparation of syn-diols | SQLE, OXER1, OXA1L | MPO 1767/4885CYP1A2 147/4885CYP2D6 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.