Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NQO1 | P15559 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222315 | 1.00 | GAA (0.60) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL4953673 | 0.88 | GAA (0.57) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL1397191 | 0.84 | GAA (0.56) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL1957427 | 0.84 | ALDH1A1 (0.49) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL7753264 | 0.80 | CA12 (0.57) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL16397724 | 0.80 | NQO1 (0.46) | GAACA12CA9KDM4ENQO1 | |
| SCHEMBL2808497 | 0.79 | KDM4E (0.57) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL30776764 | 0.79 | KDM4E (0.57) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL10702500 | 0.78 | MAPT (0.51) | GAACA12CA9KDM4EMAPT | |
| SCHEMBL1660190 | 0.78 | GAA (0.70) | GAACA12CA9KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590479-B1 | NUCLEIC ACID AMPLIFICATION | GE HEALTHCARE BIO SCIENCES (US) | 2010-11-24 | — | — | EP | disclosed |
| EP-1421213-B1 | LABELED NUCLEOSIDE POLYPHOSPHATES | GE HEALTHCARE BIO SCIENCES (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-1597602-A4 | SOLID PHASE SEQUENCING | GE HEALTHCARE BIO SCIENCES (US) | 2009-07-22 | — | — | EP | disclosed |
| US-7393640-B2 | Terminal-phosphate-labeled nucleotides with new linkers | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2008-07-01 | — | — | US | disclosed |
| EP-1592779-A4 | TERMINAL-PHOSPHATE-LABELED NUCLEOTIDES WITH NEW LINKERS | GE HEALTHCARE BIO SCIENCES (US) | 2007-12-12 | — | — | EP | disclosed |
| US-7125671-B2 | Nucleic acid amplification with terminal-phosphate labeled nucleotides | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2006-10-24 | — | — | US | disclosed |
| US-7041812-B2 | Labeled nucleoside polyphosphates | AMERSHAM BIOSCIENCES CORP (US) | 2006-05-09 | — | — | US | disclosed |
| EP-1590479-A4 | NUCLEIC ACID AMPLIFICATION | AMERSHAM BIOSCIENCES CORP (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1421213-A4 | LABELED NUCLEOSIDE POLYPHOSPHATES | AMERSHAM BIOSCIENCES CORP (US) | 2005-12-28 | — | — | EP | disclosed |
| EP-1597602-A2 | SOLID PHASE SEQUENCING | Amersham Biosciences Corp. (US) | 2005-11-23 | — | — | EP | disclosed |
| EP-1592779-A2 | TERMINAL-PHOSPHATE-LABELED NUCLEOTIDES WITH NEW LINKERS | Amersham Biosciences Corp. (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1590479-A1 | NUCLEIC ACID AMPLIFICATION | Amersham Biosciences Corp. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004071155-A2 | SOLID PHASE SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004072238-A2 | TERMINAL-PHOSPHATE-LABELED NUCLEOTIDES WITH NEW LINKERS | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | disclosed |
| WO-2004072304-A1 | NUCLEIC ACID AMPLIFICATION | AMERSHAM BIOSCIENCES CORP (US) | 2004-08-26 | — | — | WO | disclosed |
| EP-1421213-A2 | LABELED NUCLEOSIDE POLYPHOSPHATES | Amersham Biosciences Corp. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003020734-A2 | LABELED NUCLEOSIDE POLYPHOSPHATES | AMERSHAM BIOSCIENCES CORP (US) | 2003-03-13 | — | — | WO | disclosed |