Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 4/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31700363 | 0.86 | AURKA (0.60) | HSPD1HSPE1HTR6KMT2APIK3CD | |
| SCHEMBL31700702 | 0.85 | PTPN5 (0.61) | HSPD1HSPE1PKMKMT2APIK3CD | |
| SCHEMBL31700542 | 0.85 | PTPN2 (0.61) | HSPD1HSPE1PKMPIK3CDPTPN2 | |
| SCHEMBL31702052 | 0.85 | PTPN2 (0.61) | HSPD1HSPE1PKMKMT2APIK3CD | |
| SCHEMBL31701603 | 0.84 | PTPN2 (0.64) | HSPD1HSPE1SMN1; SMN2PTPN2PTPN1 | |
| SCHEMBL31701721 | 0.82 | HSPD1 (0.64) | HSPD1HSPE1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL31700367 | 0.82 | PTPN2 (0.64) | HSPD1HSPE1KMT2APTPN2PTPN1 | |
| SCHEMBL31700554 | 0.82 | PTPN2 (0.64) | HSPD1HSPE1HTR6PIK3CDSMN1; SMN2 | |
| SCHEMBL31700541 | 0.81 | HSPD1 (0.64) | HSPD1HSPE1PKMKMT2APTPN2 | |
| SCHEMBL31702050 | 0.79 | PTPN1 (0.61) | HSPD1HSPE1KMT2APIK3CDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | UNIV INDIANA TRUSTEES (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319056-A1 | METHODS FOR TREATING CANCER | HSP90AB1, HSP90B1, HSP90AB2P | HSPD1 13/4885HSPE1 9/4885POLB 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.