Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.32 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31702322 | 0.78 | CRBN (0.51) | CRBNDDB1ALDH1A1 | |
| SCHEMBL23842383 | 0.71 | CRBN (0.42) | CRBNDDB1DRD2SLC6A4ALDH1A1 | |
| SCHEMBL31709662 | 0.69 | POLB (0.42) | CRBNDDB1ALDH1A1MEN1MAPT | |
| SCHEMBL21070381 | 0.68 | CRBN (0.67) | CRBNDDB1ALDH1A1 | |
| SCHEMBL21997708 | 0.68 | CRBN (0.40) | CRBNDDB1 | |
| SCHEMBL25295415 | 0.68 | CRBN (0.67) | CRBNDDB1ALDH1A1 | |
| SCHEMBL31731147 | 0.68 | DDB1 (0.35) | CRBNDDB1DRD2SLC6A4ALDH1A1 | |
| SCHEMBL22835720 | 0.66 | CRBN (0.41) | CRBNDDB1DRD2SLC6A4 | |
| SCHEMBL31702350 | 0.65 | MEN1 (0.37) | CRBNDDB1ALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL30258093 | 0.65 | CRBN (0.40) | CRBNDDB1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250320206-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2025-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325677-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | CRBN 1627/4885CYP2A6 584/4885DDB1 3966/4885 |
| US-20250320206-A1 | STAT6 DEGRADERS | STAT6, STAT5B, STAT1 | CRBN 1627/4885CYP2A6 584/4885DDB1 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.