Bisphenol A

Bisphenol A

SCHEMBL3170263

CC(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 1.00
ESR2 Q92731 10/20 1.00
CYP3A4 P08684 4/20 1.00
HPGD P15428 2/20 1.00
HSD17B10 Q99714 2/20 1.00
AR P10275 1/20 1.00
TSHR P16473 1/20 1.00
SLC6A2 P23975 1/20 1.00
SLC6A4 P31645 1/20 1.00
HTR6 P50406 1/20 1.00
ESRRG P62508 1/20 1.00
SLC6A3 Q01959 1/20 1.00
ALDH1A1 P00352 3/20 0.80
LMNA P02545 2/20 0.68
TYR P14679 2/20 0.68
SHBG P04278 1/20 0.54
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bisphenol A SCHEMBL15062 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL278218 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL8051951 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL8058731 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL15868669 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
SCHEMBL27996 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL9774987 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL31267162 1.00 ESR1 (1.00) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL7169162 0.97 ESR1 (0.94) ESR1ESR2CYP3A4HPGDHSD17B10
Bisphenol A SCHEMBL11798493 0.97 ESR1 (0.94) ESR1ESR2CYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10167377-B2 Phosphorus containing epoxy compounds and compositions therefrom FRX POLYMERS, INC. (US) 2019-01-01 US disclosed
US-10077354-B2 Epoxy compositions FRX POLYMERS, INC. (US) 2018-09-18 US disclosed
US-9550911-B2 Fluorinated alkyl ether epoxy resin compositions and applications thereof The United States of America as represented by the Administrtor of the National Aeronautics and Space Administration (US) 2017-01-24 US disclosed
EP-3114170-A1 EPOXY COMPOSITIONS FRX Polymers, Inc. (US) 2017-01-11 EP disclosed
US-20150344748-A1 Fluorinated Alkyl Ether Epoxy Resin Compositions and Applications Thereof UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2015-12-03 US disclosed
EP-2948464-A1 PHOSPHORUS CONTAINING EPOXY COMPOUNDS AND COMPOSITIONS THEREFROM FRX Polymers, Inc. (US) 2015-12-02 EP disclosed
WO-2015134600-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-11 WO disclosed
US-20150252228-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-10 US disclosed
US-20150252175-A1 EPOXY COMPOSITIONS FRX POLYMERS, INC. (US) 2015-09-10 US disclosed
WO-2014116669-A1 PHOSPHORUS CONTAINING EPOXY COMPOUNDS AND COMPOSITIONS THEREFROM FRX POLYMERS, INC. (US) 2014-07-31 WO disclosed
US-20050208416-A1 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION 2005-09-22 US disclosed
US-20050165201-A1 Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester BORIACK CLINTON J (US) 2005-07-28 US disclosed
US-20050033094-A1 Process for preparing aryl allyl ethers BORIACK CLINTON J (US) 2005-02-10 US disclosed
US-20040049004-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom THE DOW CHEMICAL COMPANY 2004-03-11 US disclosed
US-20040024263-A1 Process for preparing aryl allyl ethers BORIACK CLINTON J (US) 2004-02-05 US disclosed
US-6646102-B2 Epoxidizing an alpha - halohydrin intermediate produced from a halide substitution of an alpha -dihydroxy derivative which has been obtained by a dihydroxylation reaction of an aryl allyl ether, oxidation catalysts DOW GLOBAL TECHNOLOGIES INC. 2003-11-11 US disclosed
US-20030149219-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom BORIACK CLINTON J (US) 2003-08-07 US disclosed
US-20030105268-A1 Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2003-06-05 US disclosed
US-6534621-B2 Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative DOW GLOBAL TECHNOLOGIES INC. 2003-03-18 US disclosed
US-20020045707-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2002-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040024263-A1 Process for preparing aryl allyl ethers PICALM, AP2M1, AP1M1 ESR1 33/4885ESR2 197/4885CYP3A4 73/4885
US-20050033094-A1 Process for preparing aryl allyl ethers PICALM, AP2M1, AP1M1 ESR1 33/4885ESR2 197/4885CYP3A4 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.