Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31703382 | 0.84 | AKR1C3 (0.41) | — | |
| SCHEMBL28376946 | 0.84 | AKR1C3 (0.41) | — | |
| SCHEMBL28381110 | 0.78 | NPC1 (0.42) | — | |
| SCHEMBL28377286 | 0.78 | NPC1 (0.42) | — | |
| SCHEMBL31703643 | 0.78 | TSHR (0.43) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2188196 | 0.74 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2FPR2 | |
| SCHEMBL2188200 | 0.74 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2FPR2 | |
| SCHEMBL2188191 | 0.74 | SLC6A4 (0.41) | SLC6A4SLC6A3SLC6A2FPR2 | |
| SCHEMBL14920733 | 0.74 | POLB (0.46) | SLC6A4SLC6A3 | |
| SCHEMBL31703519 | 0.74 | HDAC4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215536-A1 | MACROCYCLIC PANRAS INHIBITORS FOR THE TREATMENT OF CANCER | NOVARTIS AG (CH) | 2025-10-16 | — | — | WO | disclosed |