Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28381110 | 1.00 | NPC1 (0.42) | NPC1RAB9ATDP1HPGDALDH1A1 | |
| SCHEMBL28376947 | 0.83 | SLC9A1 (0.48) | TDP1HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28380943 | 0.83 | SLC9A1 (0.48) | TDP1HPGDALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31703382 | 0.79 | AKR1C3 (0.41) | HPGDALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28376946 | 0.79 | AKR1C3 (0.41) | HPGDALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL31703439 | 0.78 | SLC6A4 (0.40) | — | |
| SCHEMBL29199579 | 0.76 | LMNA (0.40) | TDP1HPGDALDH1A1SLC18A3CES1 | |
| SCHEMBL28368682 | 0.76 | SLC18A3 (0.45) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28368681 | 0.76 | SLC18A3 (0.45) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28373802 | 0.76 | SLC18A3 (0.45) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004225-A | Novel piperazine compound and preparation method and application thereof | 兰州大学 | 2020-04-14 | — | — | CN | disclosed |