Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1446325 | 0.88 | MAPT (0.59) | HSD17B10ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1686395 | 0.84 | TSHR (0.57) | ALDH1A1TSHRALOX12MAPTMEN1 | |
| SCHEMBL30342506 | 0.83 | MEN1 (0.68) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL3951892 | 0.83 | MEN1 (0.68) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL25870993 | 0.82 | CYP1A2 (0.50) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL2852704 | 0.81 | ALDH1A1 (0.82) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL31405539 | 0.80 | HSD17B10 (0.43) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL9479942 | 0.79 | ALDH1A1 (0.72) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL1118626 | 0.79 | ALDH1A1 (0.72) | HSD17B10ALDH1A1TDP1TSHRALOX12 | |
| SCHEMBL30448440 | 0.78 | ALDH1A1 (0.78) | HSD17B10ALDH1A1TDP1TSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116019794-A | Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs | 中国科学院化学研究所 | 2023-04-28 | — | — | CN | disclosed |
| EP-1377293-B1 | ARYL AND BIARYL PIPERIDINES USED AS MCH ANTAGONISTS | PHARMACOPEIA LLC (US) | 2010-03-10 | — | — | EP | disclosed |
| US-6887889-B2 | Aryl and biaryl piperdines with MCH modulatory activity | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2005-05-03 | — | — | US | disclosed |
| EP-1377293-A1 | ARYL AND BIARYL PIPERIDINES USED AS MCH ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2004-01-07 | — | — | EP | disclosed |
| US-20030013720-A1 | Aryl and biaryl piperidines with MCH modulatory activity | PHARMACOPEIA, INC. | 2003-01-16 | — | — | US | disclosed |
| WO-2002083134-A1 | ARYL AND BIARYL PIPERIDINES USED AS MCH ANTAGONISTS | PHARMACOPEIA, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| US-5344830-A | Anitinflammatory, cardiovascular, analgesic, central nervous system | MERCK & CO., INC. (US) | 1994-09-06 | — | — | US | disclosed |
| WO-1994013646-A1 | N,N-DIACYLPIPERAZINE TACHYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013720-A1 | Aryl and biaryl piperidines with MCH modulatory activity | MCHR1, MCHR2, MC5R | HSD17B10 2923/4885ALDH1A1 1096/4885TDP1 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.