Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.64 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13472387 | 0.85 | KMO (0.64) | KMOKDRMAP4K4LOXL2ALDH1A1 | |
| SCHEMBL13472368 | 0.84 | KMO (0.68) | KMOALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31706127 | 0.84 | KDR (0.48) | KMOKDRMAP4K4CKS1BSKP1 | |
| SCHEMBL13474216 | 0.82 | KMO (0.73) | KMOALDH1A1 | |
| SCHEMBL12051485 | 0.81 | GBA1 (0.57) | KDRMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL31706400 | 0.81 | KMO (0.59) | KMOMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL13472397 | 0.81 | KMO (0.56) | KMOMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL12168416 | 0.81 | KMO (0.71) | KMOALDH1A1 | |
| SCHEMBL13472369 | 0.81 | KMO (0.62) | KMOLRRK2LOXL2ALDH1A1 | |
| SCHEMBL5889086 | 0.80 | MAP4K4 (0.54) | KDRMAP4K4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |