Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704684 | 1.00 | NR1H2 (0.40) | NR1H2USP30UCHL1NAMPTPDE4B | |
| SCHEMBL31704979 | 0.85 | ESR2 (0.45) | NR1H2USP30UCHL1NAMPTESR2 | |
| SCHEMBL31704801 | 0.85 | NR1H2 (0.43) | NR1H2USP30UCHL1NAMPTESR2 | |
| SCHEMBL31706443 | 0.85 | ESR2 (0.45) | NR1H2USP30UCHL1NAMPTESR2 | |
| SCHEMBL31704569 | 0.84 | CDK7 (0.49) | USP30UCHL1NAMPT | |
| SCHEMBL31705099 | 0.81 | KDM4E (0.53) | NAMPTPDE4BKDM4EMAPTTHRB | |
| SCHEMBL31705394 | 0.81 | CHRM4 (0.34) | NAMPTTHRBALDH1A1 | |
| SCHEMBL31649256 | 0.80 | NR1H2 (0.49) | NR1H2USP30NAMPTESR2KDM4E | |
| SCHEMBL31706274 | 0.79 | NR1H2 (0.38) | NR1H2USP30UCHL1ESR2GPR119 | |
| SCHEMBL31704870 | 0.77 | PDE4B (0.48) | NR1H2USP30UCHL1PDE4BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |