Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP7 | P09237 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31704900 | 0.93 | NR1H2 (0.34) | NR1H2WDR5ESR2STSRORC | |
| SCHEMBL31705120 | 0.85 | NAMPT (0.44) | GPR119 | |
| SCHEMBL31704979 | 0.82 | ESR2 (0.45) | NR1H2WDR5ESR2PKMUSP30 | |
| SCHEMBL31706443 | 0.82 | ESR2 (0.45) | NR1H2WDR5ESR2PKMUSP30 | |
| SCHEMBL31704801 | 0.82 | NR1H2 (0.43) | NR1H2WDR5ESR2PKMUSP30 | |
| SCHEMBL31706330 | 0.79 | CDK7 (0.41) | GPR119 | |
| SCHEMBL31704684 | 0.79 | NR1H2 (0.40) | NR1H2WDR5ESR2RORCPKM | |
| SCHEMBL31705023 | 0.79 | NR1H2 (0.40) | NR1H2WDR5ESR2RORCPKM | |
| SCHEMBL31649256 | 0.77 | NR1H2 (0.49) | NR1H2ESR2PKMUSP30GPR119 | |
| SCHEMBL15649776 | 0.77 | ALDH1A1 (0.43) | NR1H2ESR2STSEPHX2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |