Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706054 | 1.00 | QDPR (0.44) | QDPRFTOSIGMAR1HTR2CTGFBR1 | |
| SCHEMBL31706444 | 0.81 | CHRM3 (0.46) | HSD17B10SLC6A3KDM4E | |
| SCHEMBL31704796 | 0.81 | CHRM3 (0.46) | HSD17B10SLC6A3KDM4E | |
| SCHEMBL18715828 | 0.77 | QDPR (0.56) | QDPRSIGMAR1HTR2CNAMPTMAPKAPK2 | |
| SCHEMBL31705007 | 0.77 | HTR2C (0.54) | QDPRSIGMAR1HTR2CNAMPT | |
| SCHEMBL3168588 | 0.77 | HTR2C (0.54) | QDPRSIGMAR1HTR2CNAMPT | |
| SCHEMBL31704650 | 0.77 | ATM (0.48) | QDPRSIGMAR1HTR2CTGFBR1ACVR1 | |
| SCHEMBL31704615 | 0.77 | TLR9 (0.44) | QDPRSIGMAR1HTR2CHSD17B10SLC6A3 | |
| SCHEMBL31704607 | 0.77 | TLR9 (0.44) | QDPRSIGMAR1HTR2CHSD17B10SLC6A3 | |
| SCHEMBL4389273 | 0.77 | CA12 (0.52) | HSD17B10SLC6A3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |