Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706047 | 0.88 | NAMPT (0.39) | NAMPTTLR9TLR8TLR7ALDH1A1 | |
| Lithium Ion SCHEMBL31704614 | 0.88 | NAMPT (0.38) | NAMPTGPR183TNKSTNKS2SCD5 | |
| Lithium Ion SCHEMBL31706176 | 0.88 | NAMPT (0.38) | NAMPTGPR183TNKSTNKS2SCD5 | |
| SCHEMBL31705199 | 0.79 | NAMPT (0.41) | NAMPTGPR183TNKSTNKS2SCD5 | |
| SCHEMBL10148409 | 0.77 | DAO (0.48) | NPC1MAPTRAB9ADAO | |
| SCHEMBL31705122 | 0.75 | TLR9 (0.44) | NAMPTSCD5SCDTLR9TLR8 | |
| SCHEMBL31705644 | 0.74 | NAMPT (0.39) | NAMPTGPR183TNKSTNKS2ALDH1A1 | |
| SCHEMBL31706109 | 0.74 | NAMPT (0.40) | NAMPTSCD5SCDTLR9TLR8 | |
| SCHEMBL31706914 | 0.73 | CNR2 (0.36) | NAMPTGPR183TNKSTNKS2ALDH1A1 | |
| SCHEMBL31704689 | 0.73 | SMYD3 (0.52) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |