Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706109 | 0.87 | NAMPT (0.40) | NAMPTHTR2BALDH1A1TLR9TLR8 | |
| Lithium Ion SCHEMBL31705499 | 0.86 | NAMPT (0.40) | NAMPTHTR2BTNKSTNKS2ALDH1A1 | |
| SCHEMBL31704523 | 0.84 | ALDH1A1 (0.42) | NAMPTALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL31704958 | 0.84 | ALDH1A1 (0.42) | NAMPTALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL31704822 | 0.80 | NAMPT (0.42) | NAMPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL31705755 | 0.79 | NAMPT (0.39) | NAMPTHTR2BTNKSTNKS2ALDH1A1 | |
| SCHEMBL31705122 | 0.77 | TLR9 (0.44) | NAMPTTLR9TLR8TLR7SCD5 | |
| Lithium Ion SCHEMBL31706119 | 0.77 | NAMPT (0.39) | NAMPTHTR2BTNKSTNKS2TLR9 | |
| Lithium Ion SCHEMBL31705497 | 0.77 | NAMPT (0.39) | NAMPTHTR2BTNKSTNKS2TLR9 | |
| SCHEMBL4392929 | 0.76 | KMO (0.55) | KMOALDH1A1HPGDTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |