Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30054277 | 0.82 | GABRA1 (0.43) | ALDH1A1KDM4EMAPTMAPK1GABRA1 | |
| SCHEMBL23885528 | 0.82 | GABRA1 (0.43) | ALDH1A1KDM4EMAPTMAPK1GABRA1 | |
| SCHEMBL6883079 | 0.81 | AURKA (0.54) | AURKAALDH1A1KDM4EMAPTCDK2 | |
| SCHEMBL30484109 | 0.81 | AURKA (0.54) | AURKAALDH1A1KDM4EMAPTCDK2 | |
| SCHEMBL6881163 | 0.81 | AURKA (0.57) | AURKAALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL14098811 | 0.77 | AURKA (0.65) | AURKAALDH1A1KDM4EMAPTGABRA1 | |
| SCHEMBL30484049 | 0.77 | AURKA (0.50) | AURKAALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL3113184 | 0.77 | AURKA (0.50) | AURKAALDH1A1BRD4GSK3BABL1 | |
| SCHEMBL25833032 | 0.77 | AURKA (0.50) | AURKAALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL2389718 | 0.76 | EGFR (0.57) | AURKAALDH1A1KDM4EMAPTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217212-A1 | MAC1 INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-16 | — | — | WO | disclosed |