Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422399 | 0.87 | HTT (0.49) | LMNATP53HTTL3MBTL1MAOB | |
| SCHEMBL5807071 | 0.83 | USP2 (0.45) | USP2MEN1KMT2ALMNAPTGDR2 | |
| SCHEMBL31706963 | 0.83 | MEN1 (0.44) | USP2MEN1KMT2ALMNAMAPT | |
| SCHEMBL18544308 | 0.82 | POLB (0.41) | LMNAPTGDR2TP53MAPTMAOB | |
| SCHEMBL31705752 | 0.81 | GAA (0.48) | MEN1KMT2AMAOBMAOA | |
| SCHEMBL15349624 | 0.80 | USP2 (0.47) | USP2MEN1KMT2ALMNAPTGDR2 | |
| SCHEMBL460339 | 0.79 | CYP1A2 (0.49) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL9885324 | 0.79 | KMT2A (0.47) | USP2MEN1KMT2ALMNAPTGDR2 | |
| SCHEMBL25528508 | 0.79 | SMN1; SMN2 (0.45) | MEN1KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL21695943 | 0.78 | USP2 (0.43) | USP2MEN1KMT2ALMNAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217552-A1 | 2-(TERT-BUTYL)-4-METHYLPHENYL APPENDED 1,4-DIAZEPANE BASED NOVEL TFEB ACTIVATING COMPOUNDS AS AUTOPHAGY MODULATORS FOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER'S DISEASE (AD) | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-10-16 | — | — | WO | disclosed |