Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.53 |
| ▸ | KDM5C | P41229 | 1/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.53 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20590890 | 1.00 | HPGD (0.67) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL14125646 | 0.85 | HPGD (0.71) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10186990 | 0.82 | SMN1; SMN2 (0.59) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10796248 | 0.82 | DDB1 (0.46) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL1648244 | 0.82 | KDM4C (0.50) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL30695503 | 0.81 | HPGD (0.70) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL28851024 | 0.81 | KDM4E (0.47) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL29185061 | 0.80 | HPGD (0.45) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL24478898 | 0.78 | HPGD (0.56) | HPGDSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL26910755 | 0.78 | HPGD (0.56) | HPGDSMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |