Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.50 |
| ▸ | KDM5B | Q9UGL1 | 6/20 | 0.50 |
| ▸ | KDM5A | P29375 | 5/20 | 0.50 |
| ▸ | KDM5C | P41229 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 3/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10796248 | 0.86 | DDB1 (0.46) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL28851024 | 0.82 | KDM4E (0.47) | KDM5AKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL20590890 | 0.82 | HPGD (0.67) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL31706136 | 0.82 | HPGD (0.67) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL16431313 | 0.80 | KDM4C (0.55) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL2096200 | 0.80 | KDM4C (0.59) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL19330255 | 0.78 | ALOX15 (0.43) | ALDH1A1NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL11504722 | 0.78 | KDM5C (0.57) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL11504717 | 0.78 | KDM4C (0.57) | KDM4CKDM5BKDM5AKDM5CKDM4E | |
| SCHEMBL29185061 | 0.77 | HPGD (0.45) | KDM4CKDM5BKDM5AKDM5CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069514-B | Antibacterial compound and application thereof | 结核病药物开发全球联盟公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-116406362-A | Spiro [3.3] heptane derivatives for the treatment and prevention of hepatitis b virus infection | 豪夫迈·罗氏有限公司 | 2023-07-07 | — | — | CN | disclosed |
| WO-2022112188-A1 | SPIRO[3.3]HEPTANE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2022-06-02 | — | — | WO | disclosed |
| US-9481675-B2 | Gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-11-01 | — | — | US | disclosed |
| WO-2011049223-A1 | COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-28 | — | — | WO | disclosed |