Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 11/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 2/20 | 0.55 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.52 |
| ▸ | AKT2 | P31751 | 2/20 | 0.51 |
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743217 | 0.84 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL2024604 | 0.82 | JAK3 (1.00) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL6742185 | 0.81 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL4053733 | 0.80 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL2016053 | 0.79 | JAK3 (1.00) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL3961208 | 0.79 | JAK3 (0.66) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL31706717 | 0.77 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL28887147 | 0.77 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL28068350 | 0.77 | JAK3 (0.67) | JAK3LCKJAK1DOT1LAKT2 | |
| SCHEMBL3956020 | 0.76 | JAK3 (0.65) | JAK3LCKJAK1DOT1LAKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217212-A1 | MAC1 INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-16 | — | — | WO | disclosed |