Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25574990 | 0.81 | AAK1 (0.49) | CACNA1HCACNA1BCACNA1CLMNAAAK1 | |
| SCHEMBL28540922 | 0.81 | SOS1 (0.40) | CACNA1HCACNA1BCACNA1CAAK1KDM4A | |
| SCHEMBL31706249 | 0.81 | PTPN7 (0.36) | LMNAEPHX2DDR1NOTUM | |
| SCHEMBL29533276 | 0.79 | AAK1 (0.45) | CACNA1HCACNA1BCACNA1CLMNAAAK1 | |
| SCHEMBL22664847 | 0.79 | AAK1 (0.45) | CACNA1HCACNA1BCACNA1CLMNAAAK1 | |
| SCHEMBL24971039 | 0.78 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CLMNAPOLB | |
| SCHEMBL31704494 | 0.78 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CKDM4AEPHX2 | |
| SCHEMBL29664091 | 0.78 | CACNA1H (0.46) | CACNA1HCACNA1BCACNA1CLMNAPOLB | |
| SCHEMBL12656366 | 0.78 | EPHX2 (0.46) | CACNA1HCACNA1BCACNA1CLMNAPOLB | |
| SCHEMBL16793735 | 0.78 | AAK1 (0.44) | CACNA1HCACNA1BCACNA1CPOLBAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215110-A1 | NEW AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS SOS1 INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2025-10-16 | — | — | WO | disclosed |