Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | CLK2 | P49760 | 2/20 | 0.33 |
| ▸ | CLK3 | P49761 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27211100 | 0.88 | KDM5C (0.35) | CYP3A4HRH1KDM5CKDM4CCXCR4 | |
| SCHEMBL16132006 | 0.83 | CCR1 (0.41) | CYP3A4CYP2D6HRH1ADORA2AADORA1 | |
| SCHEMBL3398916 | 0.83 | ADORA2A (0.41) | CYP3A4CYP2D6HRH1ADORA2AADORA1 | |
| SCHEMBL13466925 | 0.82 | CXCR4 (0.39) | CYP3A4CYP2D6HRH1ADORA2AADORA1 | |
| SCHEMBL13467135 | 0.81 | CYP3A4 (0.36) | CYP3A4CYP2D6HRH1ADORA2AADORA1 | |
| SCHEMBL29204498 | 0.79 | EGLN1 (0.44) | CYP3A4CYP2D6HRH1ADORA2AADORA1 | |
| SCHEMBL30574738 | 0.78 | SIGMAR1 (0.53) | CYP3A4CYP2D6HRH1SIGMAR1OPRM1 | |
| SCHEMBL15274470 | 0.77 | GRM2 (0.40) | ADORA2AADORA1PDCD1CD274GRM2 | |
| SCHEMBL1722737 | 0.77 | CXCR4 (0.50) | CYP2D6KDM5CKDM4CCXCR4LMNA | |
| SCHEMBL31706417 | 0.75 | ADORA2A (0.34) | CYP3A4CYP2D6HRH1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025215558-A1 | COMPOUNDS FOR SPLICING MODULATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-10-16 | — | — | WO | disclosed |