Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.61 |
| ▸ | MC5R | P33032 | 6/20 | 0.60 |
| ▸ | MC1R | Q01726 | 5/20 | 0.51 |
| ▸ | MC3R | P41968 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170726 | 1.00 | MC4R (0.61) | MC4RMC5RMC1RMC3RKCNH2 | |
| Hydrochloric Acid SCHEMBL3170453 | 0.99 | MC4R (0.63) | MC4RMC5RMC1RMC3RKCNH2 | |
| Hydrochloric Acid SCHEMBL1920194 | 0.99 | MC4R (0.63) | MC4RMC5RMC1RMC3RKCNH2 | |
| SCHEMBL6192351 | 0.88 | MC4R (0.65) | MC4RMC5RMC1RMC3R | |
| Hydrochloric Acid SCHEMBL1920855 | 0.87 | MC4R (0.64) | MC4RMC5RMC1RMC3RKCNH2 | |
| SCHEMBL1920168 | 0.86 | MC4R (0.58) | MC4RMC5RMC1RMC3RKCNH2 | |
| SCHEMBL3160673 | 0.84 | MC4R (0.51) | MC4RMC5RMC1R | |
| SCHEMBL3160669 | 0.84 | MC4R (0.51) | MC4RMC5RMC1R | |
| SCHEMBL29327329 | 0.84 | MC4R (0.51) | MC4RMC5RMC1R | |
| SCHEMBL1920280 | 0.82 | MC4R (0.60) | MC4RMC5RMC1RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7649002-B2 | (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists | PFIZER INC (US) | 2010-01-19 | — | — | US | disclosed |
| US-20050176772-A1 | Pharmaceutically active compounds | PFIZER INC | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176772-A1 | Pharmaceutically active compounds | MC4R, MC3R, MC5R | MC4R 1/4885MC5R 3/4885MC1R 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.