Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.42 |
| ▸ | CDK9 | P50750 | 4/20 | 0.42 |
| ▸ | CCND1 | P24385 | 4/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 4/20 | 0.42 |
| ▸ | CDK1 | P06493 | 3/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.42 |
| ▸ | CCND3 | P30281 | 2/20 | 0.42 |
| ▸ | CDK7 | P50613 | 2/20 | 0.42 |
| ▸ | CCNH | P51946 | 2/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707894 | 0.85 | EGFR (0.47) | CDK2CDK9CCND1CCNE1CDK6 | |
| SCHEMBL31707857 | 0.85 | CDK2 (0.45) | CDK2CDK9CCND1CCNE1CDK6 | |
| SCHEMBL30898420 | 0.84 | CDK2 (0.66) | CDK2CDK9CCND1CCNE1CDK6 | |
| SCHEMBL31707910 | 0.84 | CDK2 (0.44) | CDK2CDK9CCNE1CDK1CCNT1 | |
| SCHEMBL3306974 | 0.77 | CDK2 (0.60) | CDK2CDK9CCNE1CDK1CCNT1 | |
| SCHEMBL3299394 | 0.75 | CDK2 (0.61) | CDK2CDK9CCNE1CDK1CCNT1 | |
| SCHEMBL31707909 | 0.74 | CDK2 (0.47) | CDK2CDK9CCND1CDK6CDK1 | |
| SCHEMBL31707854 | 0.71 | CDK2 (0.42) | CDK2CDK9CCNE1CDK1CCNT1 | |
| SCHEMBL31707911 | 0.71 | CDK2 (0.42) | CDK2CDK9CCNE1CDK1CCNT1 | |
| SCHEMBL31707903 | 0.70 | CLK1 (0.56) | CDK2CDK9CCNE1CDK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634186-A1 | 2,6,9-TRISUBSTITUTED PURINES | Astrazeneca AB (SE) | 2025-10-22 | — | — | EP | disclosed |