Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.44 |
| ▸ | CDK9 | P50750 | 3/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 9/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31707857 | 0.91 | CDK2 (0.45) | CDK2CDK9CDK1EGFRCCNE1 | |
| SCHEMBL31707884 | 0.84 | CDK2 (0.42) | CDK2CDK9CDK1EGFRCCNE1 | |
| SCHEMBL31707869 | 0.84 | CDK1 (0.41) | CDK1PIK3CD | |
| SCHEMBL31707894 | 0.83 | EGFR (0.47) | CDK2CDK9CDK1EGFRCCNE1 | |
| SCHEMBL31707915 | 0.82 | CDK2 (0.56) | CDK2CDK9CDK1EGFRCCNE1 | |
| SCHEMBL3306974 | 0.82 | CDK2 (0.60) | CDK2CDK9CDK1CCNE1CCNE2 | |
| SCHEMBL3299394 | 0.80 | CDK2 (0.61) | CDK2CDK9CDK1CCNE1CCNE2 | |
| SCHEMBL31707909 | 0.80 | CDK2 (0.47) | CDK2CDK9CDK1EGFRCCNA2 | |
| SCHEMBL31707911 | 0.76 | CDK2 (0.42) | CDK2CDK9CDK1EGFRCCNE1 | |
| SCHEMBL31707854 | 0.76 | CDK2 (0.42) | CDK2CDK9CDK1EGFRCCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634186-A1 | 2,6,9-TRISUBSTITUTED PURINES | Astrazeneca AB (SE) | 2025-10-22 | — | — | EP | disclosed |