Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708108 | 0.80 | PDE2A (0.51) | POLBPDE2A | |
| SCHEMBL31708020 | 0.80 | HRH4 (0.33) | PDE2A | |
| SCHEMBL25207482 | 0.74 | KMT2A (0.30) | — | |
| SCHEMBL803483 | 0.73 | KDM4E (0.40) | HSP90AA1HSP90AB1PDE4AAGO2POLB | |
| SCHEMBL31708103 | 0.73 | KDM4E (0.33) | — | |
| SCHEMBL25216335 | 0.70 | CCR1 (0.39) | — | |
| SCHEMBL27050468 | 0.70 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1PDE4AAGO2POLB | |
| SCHEMBL24690475 | 0.70 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1PDE4AAGO2POLB | |
| SCHEMBL31708186 | 0.68 | KMT2A (0.34) | — | |
| SCHEMBL11970843 | 0.68 | KMT2A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143179-B1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-22 | — | — | EP | disclosed |