Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708065 | 0.84 | LMNA (0.42) | PDE2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL24111471 | 0.81 | PDE2A (0.46) | PDE2ARECQLKDM4EALDH1A1POLB | |
| SCHEMBL31708038 | 0.80 | HSP90AA1 (0.32) | PDE2APOLB | |
| SCHEMBL17194951 | 0.77 | PDE2A (0.48) | PDE2ARECQLKDM4EALDH1A1POLB | |
| SCHEMBL31708045 | 0.75 | CYP2C19 (0.35) | PDE2AKDM4EALDH1A1 | |
| SCHEMBL25217067 | 0.75 | CYP2C19 (0.35) | PDE2AKDM4EALDH1A1 | |
| SCHEMBL31708020 | 0.74 | HRH4 (0.33) | PDE2A | |
| SCHEMBL25239087 | 0.72 | PDE2A (0.33) | PDE2APOLB | |
| SCHEMBL13012210 | 0.72 | GAA (0.50) | PDE2AKDM4EALDH1A1POLB | |
| SCHEMBL24940652 | 0.71 | ALDH1A1 (0.42) | PDE2AKDM4EALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143179-B1 | AZETIDIN-3-YLMETHANOL DERIVATIVES AS CCR6 RECEPTOR MODULATORS FOR THE TREATMENT OF CANCER | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-10-22 | — | — | EP | disclosed |