Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | TRAP1 | Q12931 | 4/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858421 | 0.86 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1ERBB2LMNATSHR | |
| SCHEMBL30599262 | 0.85 | HSP90AB1 (0.50) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL3122649 | 0.85 | HSP90AB1 (0.50) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL1670478 | 0.78 | HSP90AB1 (0.43) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL1744449 | 0.74 | HSP90AA1 (0.57) | HSP90AA1HSP90B1 | |
| SCHEMBL1861839 | 0.71 | ERBB2 (1.00) | HSP90AA1HSP90AB1ERBB2LMNATSHR | |
| SCHEMBL13845812 | 0.71 | HSP90AB1 (0.37) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL4903368 | 0.71 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL14067096 | 0.71 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1ERBB2TRAP1HSP90B1 | |
| SCHEMBL1858420 | 0.71 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250327028-A1 | ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250327028-A1 | ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS | HSP90B1, HSP90AB1, HSP90AA1 | HSP90AA1 3/4885HSP90AB1 2/4885ERBB2 845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.