Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742802 | 1.00 | CYP3A4 (0.44) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4133359 | 0.84 | CYP3A4 (0.38) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4146714 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4016972 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1743402 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL23350070 | 0.82 | CYP3A4 (0.37) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1743405 | 0.82 | MAPT (0.47) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL31146877 | 0.82 | MAPT (0.47) | CYP3A4ABCG2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL1743404 | 0.81 | ITGB2 (0.43) | ALDH1A1HSD17B10ATMMAPTPOLB | |
| SCHEMBL3464727 | 0.78 | CYP3A4 (0.39) | CYP3A4ABCG2TAAR1MAPTSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250327028-A1 | ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250327028-A1 | ENGINEERED PLATELETS AS TARGETED PROTEIN DEGRADERS | HSP90B1, HSP90AB1, HSP90AA1 | CYP3A4 4372/4885ABCG2 3617/4885ALDH1A1 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.