Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742802 | 0.82 | CYP3A4 (0.44) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL31709528 | 0.82 | CYP3A4 (0.44) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL4133359 | 0.73 | CYP3A4 (0.38) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL4130159 | 0.73 | MAPT (0.40) | CYP3A4MAPTCYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL23350070 | 0.71 | CYP3A4 (0.37) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL1743402 | 0.71 | CYP3A4 (0.37) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL31146877 | 0.71 | MAPT (0.47) | CYP3A4ABCG2MAPTALDH1A1HSD17B10 | |
| SCHEMBL1877829 | 0.71 | CYP3A4 (0.37) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL9871731 | 0.71 | MEN1 (0.40) | CYP3A4ABCG2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL1743405 | 0.71 | MAPT (0.47) | CYP3A4ABCG2MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074126-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2008049105-A2 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | CYP3A4 4702/4885ABCG2 493/4885MAPT 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.