Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | MGAM | O43451 | 1/20 | 0.67 |
| ▸ | SI | P14410 | 1/20 | 0.67 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155563 | 0.87 | GAA (0.78) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28650988 | 0.84 | GAA (0.74) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL2593140 | 0.83 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9764489 | 0.83 | GAA (0.64) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28653298 | 0.82 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL181997 | 0.82 | GAA (0.70) | GAAMGAMSIMGAM2ALDH1A1 | |
| Malonic Acid Diethyl Ester SCHEMBL2839042 | 0.81 | GAA (0.88) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL6303688 | 0.81 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL4476235 | 0.81 | GAA (0.61) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL20299505 | 0.81 | FAAH (0.48) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118437329-A | Catalyst for preparing 2, 7-di-tert-butylpyrene by alkylation of pyrene, preparation method thereof and method for preparing 2, 7-di-tert-butylpyrene from catalyst | 北京旭阳科技有限公司 | 2024-08-06 | — | — | CN | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| CN-118437329-A | Catalyst for preparing 2, 7-di-tert-butylpyrene by alkylation of pyrene, preparation method thereof and method for preparing 2, 7-di-tert-butylpyrene from catalyst | 北京旭阳科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-107935912-A | A kind of preparation process of Amlodipine intermediate | 常州瑞明药业有限公司 | 2018-04-20 | — | — | CN | disclosed |
| WO-2015110897-A2 | NOVEL PROCESS FOR THE PREPARATION OF DOLUTEGRAVIR AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2015-07-30 | — | — | WO | disclosed |
| WO-2015038660-A1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-1553170-B1 | NOVEL CARBONYL REDUCTASE, GENE THEREOF AND METHOD OF USING THE SAME | KANEKA CORP (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-20100093817-A1 | Compounds | BIAL - PORTELA & CA S.A. (PT) | 2010-04-15 | — | — | US | disclosed |
| US-20100093817-A1 | Compounds | BIAL - PORTELA & CA S.A. (PT) | 2010-04-15 | — | — | US | disclosed |
| US-7649117-B2 | Process of preparing optically active β-hydroxycarboxylic acid derivative | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2010-01-19 | — | — | US | disclosed |
| US-7531329-B2 | Carbonyl reductase, gene thereof and method of using the same | KANEKA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| WO-2000047560-A2 | PROCESS FOR THE PREPARATION OF ASYMMETRICAL 1,4-DIHYDRO-PYRIDINE-DICARBOXYLIC ACID ESTERS | EGIS Gyógyszergyár Rt. (HU) | 2000-08-17 | — | — | WO | disclosed |
| EP-0967271-A1 | NOVEL CARBONYL REDUCTASE, GENE THAT ENCODES THE SAME, AND METHOD OF UTILIZING THESE | KANEKA CORPORATION (JP) | 1999-12-29 | — | — | EP | disclosed |
| EP-0295109-B2 | Process for preparing optically active alcohol | TAKASAGO PERFUMERY CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-4933482-A | HYDROGENATION OF BETA-KETO ACID IN PRESENCE OF RUTHENIUM PHOSPHINE COMPLEX | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0295109-A1 | Process for preparing optically active alcohol | Takasago International Corporation (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0102893-B1 | A NOVEL PRODUCTION OF 1-OXACEPHAMS | SHIONOGI & CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4539148-A | OXYGENATED BUTYRIC ACID DERIVATIVES OF OXOAZETIDINE | SHIONOGI & CO., LTD. (JP) | 1985-09-03 | — | — | US | disclosed |
| EP-0102893-A1 | A novel production of 1-oxacephams | SHIONOGI & CO., LTD. (JP) | 1984-03-14 | — | — | EP | disclosed |
| US-4421922-A | Process for the production of tetronic acid | LONZA LTD. (CH) | 1983-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093817-A1 | Compounds | TPMT, CYP2C8, ABL1 | GAA 720/4885MGAM 4178/4885SI 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.