Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 19/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710555 | 0.82 | CCNT1 (0.40) | CDK9CCNT1 | |
| SCHEMBL31710489 | 0.78 | ELANE (0.41) | — | |
| SCHEMBL31710901 | 0.76 | CCNT1 (0.40) | CDK9CCNT1NR3C1PGR | |
| SCHEMBL31710393 | 0.71 | CCNT1 (0.46) | CDK9CCNT1 | |
| SCHEMBL31710700 | 0.71 | ELANE (0.51) | — | |
| SCHEMBL16040762 | 0.68 | CCNT1 (0.62) | CDK9CCNT1 | |
| SCHEMBL31711030 | 0.68 | CCNT1 (0.41) | CDK9CCNT1NR3C1PGR | |
| SCHEMBL4726522 | 0.66 | GBA1 (0.44) | — | |
| SCHEMBL18475170 | 0.66 | NR1H2 (0.40) | — | |
| SCHEMBL18991307 | 0.65 | POLB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326773-A1 | MRGPRX2 ANTAGONISTS, PHARMACEUTICAL COMPOSITION INCLUDING MRGPRX2 ANTAGONIST, AND METHOD OF TREATING MRGPRX2-MEDIATED DISEASE OR DISORDER | KYORIN SEIYAKU KK (JP) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326773-A1 | MRGPRX2 ANTAGONISTS, PHARMACEUTICAL COMPOSITION INCLUDING MRGPRX2 ANTAGONIST, AND METHOD OF TREATING MRGPRX2-MEDIATED DISEASE OR DISORDER | MRGPRX2, MRGPRX1, MRGPRX4 | CDK9 3907/4885CCNT1 4846/4885NR3C1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.