Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637106 | 0.83 | APEX1 (0.49) | APEX1TSHRKDM4EATMMAOB | |
| SCHEMBL30637114 | 0.83 | APEX1 (0.49) | APEX1TSHRKDM4EATMMAOB | |
| SCHEMBL26679404 | 0.82 | KDM4E (0.55) | APEX1TSHRKDM4EATMMEN1 | |
| SCHEMBL16218987 | 0.80 | APEX1 (0.44) | APEX1TSHRKDM4EATMMAOB | |
| SCHEMBL19302753 | 0.80 | KDM4E (0.55) | APEX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30637088 | 0.78 | APEX1 (0.54) | APEX1TSHRKDM4EATMMAOB | |
| SCHEMBL26679499 | 0.78 | APEX1 (0.54) | APEX1TSHRKDM4EATMMAOB | |
| SCHEMBL5094363 | 0.78 | MAOB (0.50) | MAOB | |
| SCHEMBL31711021 | 0.77 | APEX1 (0.43) | APEX1TSHRKDM4EMAOBKMT2A | |
| SCHEMBL26863271 | 0.76 | APEX1 (0.51) | APEX1TSHRKDM4EATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326731-A1 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | SCRIPPS RESEARCH INST (US) | 2025-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250326731-A1 | CATALYST-CONTROLLED SITE-SELECTIVE METHYLENE C-H LACTONIZATION OF DICARBOXYLIC ACIDS | DNPH1, NISCH, PTMA | APEX1 2689/4885TSHR 4726/4885KDM4E 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.