SCHEMBL31712151

SCHEMBL31712151

CC(C)(C)[Si](C)(C)OCCOCCON1C(=O)c2ccccc2C1=O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.67
ALDH1A1 P00352 4/20 0.58
DUT P33316 2/20 0.47
RECQL P46063 1/20 0.44
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
CYP1A2 P05177 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
HTT P42858 1/20 0.39
CYP2C9 P11712 1/20 0.38
ATM Q13315 1/20 0.37
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9544542 0.96 GAA (0.58) GAAALDH1A1DUTRECQLMEN1
SCHEMBL4851745 0.87 RECQL (0.55) GAAALDH1A1DUTRECQLMEN1
SCHEMBL12767494 0.87 GAA (0.51) GAAALDH1A1DUTRECQLMEN1
SCHEMBL14057890 0.84 GAA (0.48) GAAALDH1A1DUTRECQLMEN1
SCHEMBL18419336 0.83 DUT (0.47) GAAALDH1A1DUTKMT2AMAPT
SCHEMBL12028883 0.82 GAA (1.00) GAAALDH1A1RECQLMEN1KMT2A
SCHEMBL3077457 0.82 GAA (1.00) GAAALDH1A1RECQLMEN1KMT2A
SCHEMBL12029057 0.82 GAA (1.00) GAAALDH1A1RECQLMEN1KMT2A
SCHEMBL17641579 0.78 GAA (0.43) GAAALDH1A1DUTRECQLMEN1
SCHEMBL24181345 0.77 GAA (0.83) GAAALDH1A1RECQLMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4640688-A1 AVERMECTIN DERIVATIVE Meiji Seika Pharma Co., Ltd. (JP) 2025-10-29 EP disclosed