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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL31716908

O=C(NCc1ccc(Cl)cc1OC(F)(F)F)N1CC2(CCNCC2)C1.O=C(O)C(F)(F)F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 11/20 0.48
▸ DDR1 Q08345 3/20 0.45
▸ HTR2C P28335 1/20 0.43
▸ HTR2B P41595 1/20 0.43
▸ ENPP2 Q13822 2/20 0.42
▸ ATXN2 Q99700 2/20 0.42
▸ CCR4 P51679 1/20 0.40
▸ GPR183 P32249 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31716874 0.86 EPHX2 (0.48) EPHX2DDR1HTR2CHTR2BCCR4
SCHEMBL31717291 0.84 EPHX2 (0.53) EPHX2DDR1GPR183
SCHEMBL31716807 0.82 EPHX2 (0.49) EPHX2DDR1ENPP2ATXN2
SCHEMBL31716867 0.80 EPHX2 (0.54) EPHX2DDR1
Trifluoroacetic Acid SCHEMBL31717317 0.75 TACR1 (0.48) ENPP2ATXN2
Trifluoroacetic Acid SCHEMBL31717830 0.75 USP2 (0.41) EPHX2ENPP2ATXN2GPR183
Trifluoroacetic Acid SCHEMBL31716872 0.74 P2RX7 (0.46) EPHX2ENPP2ATXN2GPR183
SCHEMBL31717481 0.73 KCNH2 (0.53) EPHX2DDR1
Trifluoroacetic Acid SCHEMBL30140975 0.73 CYP2D6 (0.56) EPHX2
Trifluoroacetic Acid SCHEMBL30140971 0.73 CYP2D6 (0.56) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224085-A1 COMPOUNDS CAPABLE OF ACTING ON S1R AS WELL AS ON SEH AND USES THEREOF UNIVERSITAT DE BARCELONA (ES) 2025-10-30 — — WO disclosed
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