SCHEMBL31717138

SCHEMBL31717138

COC(=O)c1cnc(Nc2ccccc2)c(N)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 2/20 0.56
KDR P35968 2/20 0.56
MAPT P10636 6/20 0.50
MAPK1 P28482 5/20 0.50
POLB P06746 1/20 0.50
KDM4E B2RXH2 5/20 0.48
ALDH1A1 P00352 3/20 0.48
GAA P10253 3/20 0.48
HPGD P15428 3/20 0.48
PKM P14618 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
CSNK2A1 P68400 1/20 0.47
TSHR P16473 2/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
PDE5A O76074 2/20 0.44
HSD17B10 Q99714 2/20 0.44
THRB P10828 1/20 0.44
ABCC1 P33527 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13202023 0.88 MAPK1 (0.52) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL23675260 0.86 MAPT (0.51) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL29996009 0.86 MAPT (0.51) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL23675301 0.86 MAPT (0.51) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL21811833 0.86 MAPK1 (0.48) PDGFRBKDRMAPTMAPK1KDM4E
SCHEMBL3636023 0.83 MAPT (0.56) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL25112148 0.83 RXFP1 (0.47) MAPTKDM4EALDH1A1GAAHPGD
SCHEMBL23675170 0.83 MAPT (0.48) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL30361455 0.83 MAPT (0.48) PDGFRBKDRMAPTMAPK1POLB
SCHEMBL25175607 0.83 MAPT (0.47) PDGFRBKDRMAPTMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224308-A1 QPCTL INHIBITORS SCENIC IMMUNOLOGY B.V. (NL) 2025-10-30 WO disclosed