Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 13/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31717138 | 0.86 | PDGFRB (0.56) | MAPK1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL23675301 | 0.85 | MAPT (0.51) | MAPK1L3MBTL1EGFRMAPTSMN1; SMN2 | |
| SCHEMBL30509795 | 0.81 | MAPK1 (0.72) | MAPK1L3MBTL1EGFRMAPT | |
| SCHEMBL21811853 | 0.81 | MAPK1 (0.72) | MAPK1L3MBTL1EGFRMAPT | |
| SCHEMBL13202023 | 0.80 | MAPK1 (0.52) | MAPK1L3MBTL1EGFRMAPTMEN1 | |
| SCHEMBL2666277 | 0.79 | GAA (0.58) | MAPK1L3MBTL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL29996009 | 0.79 | MAPT (0.51) | MAPK1L3MBTL1EGFRMAPTSMN1; SMN2 | |
| SCHEMBL23675260 | 0.79 | MAPT (0.51) | MAPK1L3MBTL1EGFRMAPTSMN1; SMN2 | |
| SCHEMBL25352431 | 0.78 | MAPK1 (0.49) | MAPK1L3MBTL1EGFRMAPTNPC1 | |
| SCHEMBL14852208 | 0.76 | NPC1 (0.52) | MAPTSMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112714765-B | GABA A Receptor ligands | 萨尼奥纳有限责任公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-3849976-B1 | A GABA A RECEPTOR LIGAND | SANIONA AS (DK) | 2022-10-26 | — | — | EP | disclosed |
| US-11396510-B2 | GABAA receptor ligand | SANIONA A/S (DK) | 2022-07-26 | — | — | US | disclosed |
| US-20210332042-A1 | A GABAA Receptor Ligand | SANIONA A/S (DK) | 2021-10-28 | — | — | US | disclosed |
| US-20210332042-A1 | A GABAA Receptor Ligand | SANIONA A/S (DK) | 2021-10-28 | — | — | US | disclosed |
| EP-3849976-A1 | A GABA A RECEPTOR LIGAND | Saniona A/S (DK) | 2021-07-21 | — | — | EP | disclosed |
| CN-112714765-A | GABAAReceptor ligands | 萨尼奥纳有限责任公司 | 2021-04-27 | — | — | CN | disclosed |
| WO-2020053377-A1 | A GABAA RECEPTOR LIGAND | SANIONA A/S (DK) | 2020-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332042-A1 | A GABAA Receptor Ligand | GABRA2, GABRA6, GABRA5 | MAPK1 4095/4885L3MBTL1 2483/4885EGFR 560/4885 |
| US-11396510-B2 | GABAA receptor ligand | GABRA2, GABRA3, GABRA6 | MAPK1 4197/4885L3MBTL1 2359/4885EGFR 543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.