SCHEMBL317172

SCHEMBL317172

[CH2]C(O)(CC)OC(=O)C=C

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.42
TSHR P16473 8/20 0.41
HPGD P15428 1/20 0.41
ALDH1A1 P00352 6/20 0.36
TP53 P04637 3/20 0.36
HIF1A Q16665 3/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27970264 0.83 TSHR (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28385365 0.82 THRB (0.44) THRBTSHRHPGDALDH1A1TP53
SCHEMBL23827185 0.80 THRB (0.47) THRBTSHRHPGDALDH1A1TP53
SCHEMBL31390458 0.80 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28821821 0.80 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL996460 0.80 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL466005 0.78 THRB (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL28060416 0.78 THRB (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1706295 0.77 THRB (0.44) THRBTSHRHPGDALDH1A1TP53
SCHEMBL1108022 0.77 THRB (0.44) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2983618-B1 PHAKIC LENS DEVICE WITH OPENINGS AND CONCENTRIC ANNULAR ZONES DAVE JAGRAT NATAVAR (IN) 2019-04-17 EP disclosed
US-20170304047-A1 INTRAOCULAR LENS CUSTOMIZED FOR ASTIGMATISM OR COMBINED ASTIGMATISM AND PRESBYOPIA DAVE, JAGRAT NATAVAR (IN) 2017-10-26 US disclosed
EP-3188690-A1 INTRAOCULAR LENS CUSTOMIZED FOR ASTIGMATISM OR COMBINED ASTIGMATISM AND PRESBYOPIA Dave, Jagrat Natavar (IN) 2017-07-12 EP disclosed
US-20170181847-A1 POLYMERIC COMPOSITION FOR OCULAR DEVICES DAVE, Jagrat Natavar (IN) 2017-06-29 US disclosed
US-9622853-B2 Polymeric composition for ocular devices DAVE, Jagrat Natavar (IN) 2017-04-18 US disclosed
US-20160220348-A1 REFRACTIVE-DIFFRACTIVE OPHTHALMIC DEVICE AND COMPOSITIONS USEFUL FOR PRODUCING SAME DAVE, Jagrat Natavar (IN) 2016-08-04 US disclosed
EP-2591026-B1 REFRACTIVE-DIFFRACTIVE OPHTHALMIC DEVICE AND COMPOSITIONS USEFUL FOR PRODUCING SAME DAVE JAGRAT NATAVAR (IN) 2016-05-04 EP disclosed
US-9310624-B2 Refractive-diffractive ophthalmic device and compositions useful for producing same Jagrat Natavar DAVE (IN) 2016-04-12 US disclosed
WO-2016034925-A1 INTRAOCULAR LENS CUSTOMIZED FOR ASTIGMATISM OR COMBINED ASTIGMATISM AND PRESBYOPIA DAVE, JAGRAT NATAVAR (IN) 2016-03-10 WO disclosed
US-20160058552-A1 PHAKIC LENS DEVICE WITH OPENINGS AND CONCENTRIC ANNULAR ZONES DAVE, JAGRAT NATAVAR (IN) 2016-03-03 US disclosed
CN-102741055-A Coating agent for forming inkjet ink receiving layer, recording medium using same, and printed matter TOYO INK SC HOLDINGS CO LTD 2012-10-17 CN disclosed
CN-101238158-B Repellent composition containing graft copolymer, and method for producing the same DAIKIN IND LTD 2012-05-30 CN disclosed
CN-102365586-A Photosensitive coloring composition and color filter TOYO INK SC HOLDINGS CO LTD 2012-02-29 CN disclosed
WO-2012004746-A2 REFRACTIVE-DIFFRACTIVE OPHTHALMIC DEVICE AND COMPOSITIONS USEFUL FOR PRODUCING SAME POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO disclosed
WO-2012004744-A2 POLYMERIC COMPOSITION FOR OCULAR DEVICES POLYMER TECHNOLOGIES INTERNATIONAL (EOU) (IN) 2012-01-12 WO disclosed
CN-101223198-B Curable composition, cured film, and laminate TOYO INK MANUFACTURING CO.,LTD. (JP) 2011-12-28 CN disclosed
CN-101441413-A Green colored composition for color filter and color filter TOYO INK MFG CO (JP) 2009-05-27 CN disclosed
CN-101397424-A Ink composition FUJIFILM CORP (JP) 2009-04-01 CN disclosed
CN-101238158-A Repellent composition containing graft copolymer, graft copolymer and method of preparing graft copolymer DAIKIN IND LTD (JP) 2008-08-06 CN disclosed
CN-101223198-A Curable composition, cured film, and laminate TOYO INK MFG CO (JP) 2008-07-16 CN disclosed