Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055302 | 1.00 | LMNA (0.37) | LMNANR1I2AHRPDK2PDK4 | |
| SCHEMBL31484426 | 0.86 | TDP1 (0.35) | LMNAPDK2PDK4TDP1 | |
| SCHEMBL14970132 | 0.80 | LMNA (0.46) | LMNANR1I2AHRTDP1 | |
| SCHEMBL4068928 | 0.79 | LMNA (0.37) | LMNANR1I2AHR | |
| SCHEMBL29350081 | 0.79 | LMNA (0.37) | LMNANR1I2AHR | |
| SCHEMBL31484438 | 0.77 | KMT2A (0.44) | LMNANR1I2AHR | |
| SCHEMBL7333666 | 0.75 | — | — | |
| SCHEMBL1983684 | 0.75 | NR1I2 (0.47) | LMNANR1I2AHR | |
| SCHEMBL1830615 | 0.72 | PDE10A (0.37) | LMNAPDK2PDK4TDP1 | |
| SCHEMBL10376639 | 0.72 | LMNA (0.50) | LMNAPDK2PDK4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642782-A2 | ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF | Pliant Therapeutics, Inc. (US) | 2025-11-05 | — | — | EP | disclosed |