SCHEMBL31718378

SCHEMBL31718378

O=C(Oc1c(F)c(F)c(F)c(F)c1F)N1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
POLB P06746 1/20 0.55
SMN1; SMN2 Q16637 5/20 0.47
MAPT P10636 4/20 0.47
NPC1 O15118 3/20 0.47
HTT P42858 2/20 0.47
RAB9A P51151 2/20 0.47
TSHR P16473 2/20 0.47
NPSR1 Q6W5P4 4/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
LIPA P38571 3/20 0.42
TDP1 Q9NUW8 2/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31034735 0.83 NCEH1 (0.43) ALDH1A1POLBSMN1; SMN2MAPTNPC1
SCHEMBL19704125 0.79 GAA (0.57) ALDH1A1SMN1; SMN2NPC1RAB9ANPSR1
SCHEMBL31034525 0.78 MEN1 (0.40) ALDH1A1POLBSMN1; SMN2MAPTNPC1
SCHEMBL19704135 0.75 CYP2D6 (0.43) SMN1; SMN2MAPTNPC1HTTRAB9A
SCHEMBL16965799 0.74 ALDH1A1 (0.58) ALDH1A1POLBSMN1; SMN2MAPTNPC1
SCHEMBL10708008 0.73 ALDH1A1 (0.32) ALDH1A1POLBLMNA
SCHEMBL12038930 0.72 ALDH1A1 (0.42) ALDH1A1POLBSMN1; SMN2MAPTNPC1
SCHEMBL27795067 0.72 ALDH1A1 (0.82) ALDH1A1POLBSMN1; SMN2MAPTNPC1
SCHEMBL14659759 0.71 CA1 (0.33)
SCHEMBL830024 0.71 NPSR1 (0.64) ALDH1A1POLBSMN1; SMN2MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4696312-A1 ANTI-TROP2 ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2026-02-18 EP claimed
EP-4643889-A1 ANTI-5T4 ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2025-11-05 EP claimed
EP-4643886-A1 ANTI-CD33/CLL1 BISPECIFIC ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2025-11-05 EP claimed
EP-4696312-A1 ANTI-TROP2 ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2026-02-18 EP disclosed
EP-4643889-A1 ANTI-5T4 ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2025-11-05 EP disclosed
EP-4643886-A1 ANTI-CD33/CLL1 BISPECIFIC ANTIBODY-NATURAL KILLER CELL CONJUGATE AND USE THEREOF IMBIORAY (HANGZHOU) BIOMEDICINE CO., LTD. (CN) 2025-11-05 EP disclosed