SCHEMBL31718445

SCHEMBL31718445

CCCOc1ccc2c(c1)CCC(=O)N2

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 17/20 0.67
MAOA P21397 15/20 0.67
PDE3B Q13370 2/20 0.56
PDE3A Q14432 2/20 0.56
HTR1A P08908 1/20 0.53
DRD2 P14416 1/20 0.53
DRD4 P21917 1/20 0.53
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
SLC6A4 P31645 1/20 0.53
HTR7 P34969 1/20 0.53
DRD3 P35462 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12359302 0.94 MAOB (0.70) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL13111961 0.90 MAOB (0.65) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL2205572 0.88 MAOA (0.66) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL11768557 0.87 MAOB (0.63) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL25362567 0.85 MAOB (0.67) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL10900923 0.85 MAOB (0.67) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL426467 0.85 MAOB (0.70) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL6583075 0.85 MAOB (0.67) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL11282730 0.85 MAOB (0.63) MAOBMAOAPDE3BPDE3AHTR1A
SCHEMBL31718498 0.85 MAOB (0.63) MAOBMAOAPDE3BPDE3AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229046-A1 SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME MOLIUS SAGLIK TEKNOLOJILERI ANONIM SIRKETI (TR) 2025-11-06 WO disclosed
EP-4644375-A1 SUBSTITUTED HYDROQUINOLINES FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME Molius Saglik Teknolojileri Anonim Sirketi (TR) 2025-11-05 EP disclosed