SCHEMBL31721186

SCHEMBL31721186

CCOC(=O)[C@H](CCc1ccc(-c2ccccc2)cc1)N[C@@H](C)C(=O)N1CCCC1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACE P12821 12/20 0.63
LMNA P02545 2/20 0.63
ABCB11 O95342 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
USP2 O75604 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
PDE3A Q14432 1/20 0.51
NAAA Q02083 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19645413 0.94 ACE (0.69) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL20227445 0.83 ACE (0.67) ACELMNA
SCHEMBL16624673 0.82 ACE (0.56) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL13173445 0.81 ACE (0.69) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL13930194 0.80 ACE (0.52) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL10961687 0.79 ACE (0.94) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL20218251 0.79 ACE (0.63) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL4671537 0.78 ACE (0.61) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL4671532 0.78 ACE (0.61) ACELMNAABCB11SMN1; SMN2MEN1
SCHEMBL10729338 0.78 ACE (0.60) ACELMNAABCB11SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229501-A1 PHARMACEUTICAL COMPOSITION COMPRISING ENALAPRIL MALEATE, USE AND PREPARATION METHOD LABORATORIOS ANDRÓMACO S.A. (CL) 2025-11-06 WO disclosed