Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 4/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 2/20 | 0.34 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746268 | 0.78 | JAK2 (0.36) | JAK2PDPK1IKBKBILKAURKA | |
| SCHEMBL14813996 | 0.78 | JAK2 (0.36) | JAK2PDPK1IKBKBAURKATGFBR1 | |
| SCHEMBL7257406 | 0.71 | GSK3A (0.55) | HPGDLMNAALDH1A1JAK2PDPK1 | |
| SCHEMBL11231797 | 0.70 | PDE3B (0.54) | JAK2PDPK1AURKB | |
| SCHEMBL7256732 | 0.70 | KDM4E (0.44) | DYRK1AMEN1KMT2A | |
| SCHEMBL7256564 | 0.69 | GSK3A (0.58) | PDPK1MAPK1 | |
| SCHEMBL18130782 | 0.69 | JAK2 (0.53) | JAK2PDPK1IKBKBCHUKAURKA | |
| SCHEMBL25366182 | 0.69 | GAA (0.58) | HPGDLMNAALDH1A1JAK2ILK | |
| SCHEMBL30588978 | 0.69 | GAA (0.58) | HPGDLMNAALDH1A1JAK2ILK | |
| SCHEMBL29693601 | 0.69 | LMNA (0.46) | HPGDLMNAALDH1A1APOBEC3GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025228900-A1 | ARYLAMIDE SUBSTITUTED INDAZOLES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-11-06 | — | — | WO | disclosed |